I don't know if I can get caught up in all the "Runner's High" theories such as Endorphins and Cannabinoids. Heck, I can barely spell those words! Since the 1980's, many believed that Endorphins acted as an internal morphine-like response to pain in your body when running long distances. In the early 2000's this theory was discredited by a research that determined that the molecules associated to Endorphins were to large to pass through the Brain-barrier. The latest theories are associated to Cannabinoids, a new neuro-based chemical system composed of molecules known as lipids. These lipids are small enough to pass through the Brain-barrier and stimulate the body with a similar effect as marijuana.
I just don't buy it! I believe when you run, its all psychological. When you have a good run, you feel good. When you diet right and lose weight you feel good. When you meet your goals, you feel good. When you sweat out all your toxins, you feel good. When you run, you get in a trance, and you feel good. But remember, sometimes you feel bad too. When you run, your foot hurts. When you run, your back hurts. When you run, your knee hurts.
Its all about the psyche. When you run, the impacts can vary from person to person. For me, running usually helps me with thinking through problems, helps me get rid of the stresses of the day, and definitely helps me with losing weight and feeling good about it! If that's the so-called "Runner's High," then I'm addicted!